Forschung und Publikationen Tumororthopädie

2025

1 . Dürr HR, Hett M, Klein A, Rakete S, Holzapfel BM, Lahr C. Highly Elevated Metal Ion Levels After Tumor Resections and Reconstruction With Megaprostheses Around the Knee. Clin Orthop Relat Res. 2025 Apr 23. doi: 10.1097/CORR.0000000000003515. Epub ahead of print. PMID: 40279194.

2. Burkhard-Meier A, Rechenauer VV, Berclaz LM, Jurinovic V, Albertsmeier M, Dürr HR, Güler SE, Hoberger M, Klein A, Knösel T, Kunz WG, Schmidt-Hegemann NS, Von Bergwelt-Baildon M, Lindner LH, Di Gioia D. Maintenance treatment with trofosfamide in patients with advanced soft tissue sarcoma - a retrospective single-centre analysis. Acta Oncol. 2025 Jan 15;64:56-62.

3. Erber B, Geßl A, Reidler P, Dürr HR, Klein A, Seidensticker M, Wildgruber M, Ricke J, Sabel B. Impact of reactive sclerosis on outcome of MR-HIFU for osteoid osteomas. Eur J Radiol. 2025 Feb;183:111902. doi: 10.1016/j.ejrad.2024.111902. Epub 2024 Dec 26. PMID: 39753004.

4. Burkhard-Meier A, Rechenauer VV, Jurinovic V, Albertsmeier M, Hoberger M, Dürr HR, Klein A, Knösel T, Kunz WG, Mock A, Pusztai A, Völkl M, von Bergwelt-Baildon M, Lindner LH, Di Gioia D, Berclaz LM. First-line pazopanib in patients with metastatic epithelioid hemangioendothelioma: a retrospective single-center analysis. J Cancer Res Clin Oncol. 2025 Apr 26;151(4):150. doi: 10.1007/s00432-025-06208-8. PMID: 40285941; PMCID: PMC12033179.

5. Berclaz LM, Di Gioia D, Völkl M, Jurinovic V, Klein A, Dürr HR, Knösel T, Teodorescu B, Enßle S, Rippl M, von Bergwelt-Baildon M, Kunz WG, Lindner LH, Burkhard-Meier A. The impact of CT-based adipose tissue distribution and sarcopenia on treatment outcomes in patients with high-risk soft tissue sarcoma. BMC Cancer. 2025 Apr 11;25(1):671. doi: 10.1186/s12885-025-14050-x. PMID: 40217461; PMCID: PMC11992814.

6. Gassert FG, Lang D, Hesse N, Dürr HR, Klein A, Kohll L, Hinterwimmer F, Luitjens J, Weissinger S, Peeken JC, Mogler C, Knebel C, Bartzsch S, Gassert FT, Gersing AS. A deep learning model for classification of chondroid tumors on CT images. BMC Cancer. 2025 Mar 28;25(1):561. doi: 10.1186/s12885-025-13951-1. PMID: 40155859; PMCID: PMC11951610.

7. Berclaz LM, Di Gioia D, Jurinovic V, Völkl M, Güler SE, Albertsmeier M, Klein A, Dürr HR, Mansoorian S, Knösel T, Kunz WG, von Bergwelt-Baildon M, Lindner LH, Burkhard-Meier A. LDH and hemoglobin outperform systemic inflammatory indices as prognostic factors in patients with soft tissue sarcoma undergoing neoadjuvant treatment. BMC Cancer. 2025 Mar 18;25(1):496. doi: 10.1186/s12885-025-13889-4. PMID: 40102864; PMCID: PMC11916319.

8. Berclaz LM, Jurinovic V, Burkhard-Meier A, Abdel-Rahman S, Albertsmeier M, Klein A, Dürr HR, Schmidt-Hegemann NS, Knösel T, Kunz WG, Stutz E, von Bergwelt-Baildon M, Di Gioia D, Lindner LH. Doxorubicin Plus Dacarbazine Versus Doxorubicin Plus Ifosfamide in Combination With Regional Hyperthermia in Patients With Advanced Leiomyosarcoma: A Propensity Score-Matched Analysis. Cancer Med. 2025 Feb;14(4):e70655. doi: 10.1002/cam4.70655. PMID: 40007213; PMCID: PMC11861570.

9. Klein A, Dürr HR. SOP Pathologische Frakturen der Extremitätenknochen. Orthopädie und Unfallchirurgie up2date 2025; 20(05): 453-458

10. Bode-Lesniewska B, Dürr HR, Wang D, Naghavi A, Montreuil J, Fischer T, Ghert M, Lazarides A, Lindner L, Martin-Broto J, Mazza M, Scanferla R, Studer G, Temple HT, Wunder J, Fuchs B. Rethinking the Prognostic Role of Necrosis in Soft-Tissue Sarcoma: Multidisciplinary Insights from the Sarcoma Academy. Cancers (Basel). 2025 May 26;17(11):1779. doi: 10.3390/cancers17111779. PMID: 40507260; PMCID: PMC12153611.

11. Burkhard-Meier A, Grube M, Jurinovic V, Agaimy A, Albertsmeier M, Berclaz LM, Di Gioia D, Dürr HR, von Eisenhart-Rothe R, Eze C, Fechner K, Fey E, Güler SE, Hecker JS, Hendricks A, Keil F, Klein A, Knebel C, Kovács JR, Kunz WG, Lenze U, Lörsch AM, Lutz M, Meidenbauer N, Mogler C, Schmid S, Schmidt-Hegemann NS, Schneider C, Semrau S, Sienel W, Trepel M, Waldschmidt J, Wiegering A, Lindner LH. Does Size Outweigh Number in Predicting Survival After Pulmonary Metastasectomy for Soft Tissue Sarcoma? Insights from a Retrospective Multicenter Study. Ann Surg Oncol. 2025 Aug;32(8):5948-5956. doi: 10.1245/s10434-025-17450-2. Epub 2025 May 14. PMID: 40369396; PMCID: PMC12222427.

12. Burkhard-Meier A, Rechenauer VV, Jurinovic V, Albertsmeier M, Hoberger M, Dürr HR, Klein A, Knösel T, Kunz WG, Mock A, Pusztai A, Völkl M, von Bergwelt-Baildon M, Lindner LH, Di Gioia D, Berclaz LM. First-line pazopanib in patients with metastatic epithelioid hemangioendothelioma: a retrospective single-center analysis. J Cancer Res Clin Oncol. 2025 Apr 26;151(4):150. doi: 10.1007/s00432-025-06208-8. PMID: 40285941; PMCID: PMC12033179.


2026

Hoberger M, Zuber RL, Burkhard-Meier A, Di Gioia D, Jurinovic V, Völkl M, Güler SE, Albertsmeier M, Klein A, Dürr HR, Schmidt-Hegemann NS, Knösel T, Kunz WG, von Bergwelt-Baildon M, Lindner LH, Berclaz LM. Long-term benefit from high-dose ifosfamide in sarcoma depends on sustained prior control and timely intervention: a machine learning analysis. J Cancer Res Clin Oncol. 2026 Jan 8;152(1):34. doi: 10.1007/s00432-025-06410-8. PMID: 41504936; PMCID: PMC12783467.

Stadelmeier J, Bijeljac F, Klein A, Winden F, Reidler P, Dürr HR. TGCT of the shoulder - a case series and literature review. Arch Orthop Trauma Surg. 2026 Mar 9;146(1):105. doi: 10.1007/s00402-026-06237-z. PMID: 41801507; PMCID: PMC12971862.

Albertsmeier M, Milani V, Lindner LH, Tinè G, Pasquali S, Callegaro D, Gronchi A, Dürr HR, Klein A, Di Gioia D, Abdel-Rahman S, Schmidt M, Werner J, von Bergwelt-Baildon M, Miceli R, Issels R. Neoadjuvant chemotherapy for soft-tissue sarcoma of the extremities: A post-hoc Sarculator-based risk analysis of the EORTC 62961-ESHO 95 randomized trial. Cancer. 2026 May 1;132(9):e70427. doi: 10.1002/cncr.70427. PMID: 42035475; PMCID: PMC13110853.

Jeys LM, Botello E, Boyle R, Ebeid W, Hilton T, Houdek MT, Hosking K, Kurisunkal VJ, Laubscher M, Morris GV, Puri A, Ruggieri P; BOOM 2026 Consensus Meeting Participants; Laitinen MK, Abdul Bari Y, Abood A, Abraham JA, Acosta Marin M, Agarwal M, Agarwal R, Aguirre M, Ajit Singh V, Akiyama T, Al Farii H, Alaqeel M, Alaseem A, Aldosari O, Alexander K, Alfaro P, Aljuhani W, Allison DC, Almashahedi M, Alotaibi A, Alpan B, Alshaygy IS, Althunayan T, Andreani L, Andreou D, Andriandi A, Annabelle L, Aponte-Tinao L, Ardelt M, Armas S, Aston W, Aycan OE, Baad-Hansen T, Baeza P, Baird C, Balach T, Banse X, Barriga J, Barry J, Basile G, Bastoni S, Basuki MH, Bauer HC, Baydar S, Bayliss L, Becker R, Bedi A, Benevenia J, Bengoa F, Berger C, Bernthal N, Binitie O, Bird J, Bobseit A, Bodian C, Boffano M, Bonilla Huertas P, Bramer J, Broadhead M, Broekhuis D, Broida SE, Brown D, Bruschi A, Budny T, Buist M, Burke Z, Busse T, Cabrolier J, Calvo-Haro JA, Campanacci DA, Cardoso R, Carey Smith R, Carrasco MG, Casales N, Castan A, Ceballos O, Chan CM, Chan L, Chang LZ, Charoenlap C, Chaustre Florez JF, Chin J, Choong P, Chrobok A, Chung YG, Ciechanowicz D, Clara-Altamirano MA, Consuegra Guzman LA, Cornu O, Coubeau L, Courtot L, Crawford B, Cribb G, Cuervo-Lozano CE, Dammerer D, de la Rosa P, de Lima Corvino D, De Paolis M, De Santos de la Fuente FJ, de Vaal M, Deisenhofer JM, Delgado Obando J, Demir E, Deo S, Deventer N, Di Bella C, Dierselhuis E, Docquier PL, Domson G, Donati DM, Doshi A, Duivenvoorden MJC, Duran-Ciarrochi R, Dürr HR, Ehlers PJ, El Ghoneimy AM, El Motassime A, Eloi Pinto FF, Endo M, Epstein G, Eralp L, Etaiwi M, Eward W, Fabbri N, Faimali M, Farman U, Farooq A, Farooque K, Farris C, Ferguson P, Ferreira N, Fiorenza F, Flint M, Forsberg JA, Franks D, Freitas JP, Fuchs B, Fujiwara T, Funovics PT, Fuzy E, Galli Serra M, Gamie Z, Garcia-Carrasco M, García-Huidobro G, Gaston CL, Gazendam A, Georges B, Ghert M, Ghosh KM, Giardina FL, Gibbs CP, Golovina Y, Gomez Mier LC, Gomez-Mascard A, Gomez-Sierra MA, González-Browne C, Gonzalez-Saldivar J, González-Motta A, Gortzak Y, Gosheger G, Gouin F, Goulding K, Gracia I, Graydon A, Green N, Griffin A, Guedes A, Gulia A, Gupta S, Guzman M, Hardes J, Hasan YO, Hashim AM, Havard H, Haydon R, Hegde P, Hernandez Lopez A, Herrera D, Hesham A, Hesla A, Hess M, Hirschmann A, Hobusch G, Hohensteiner A, Hongsaprabhas C, Hornicek F, Hsu M, Idowu OK, Idulhaq M, Igbinoba B, Ippolito JA, Iwata S, Jagiello J, Johan MP, Johnson L, Johnston A, Joo MW, Joyce D, Jung B, Jungels C, Jutte P, Jutte W, Jääskeläinen AS, Kaldas K, Kapanci B, Karaca MO, Kawai A, Kemp A, Khal AA, Khan Z, Khan ZA, Khaouam N, Kim HS, Klopper S, Kobayashi E, Kobayashi H, Kontogeorgakos V, Kotrych D, Krebbekx GGJ, Krishnamurthy AV, Kunisada T, Kyte R, Lacroix V, Lazarides A, Le Nail LR, Lee FY, Lee J, Lee M, Legosz P, Lehner B, Leithner A, Leone G, Letson D, Lewis VO, Li B, Liikanen H, Lin P, Linda Z, Lindsay S, Lozano Calderon S, Lutomia Lumbasi M, Macdonald J, Machado P, Majirija E, Malina M, Malyk R, Marais L, Mascard E, Mattei JC, McCullough L, McMahon S, Medellin Rincon MR, Mediavilla Santos L, Meijer D, Meijer JG, Miller B, Molloy A, Moriel Garcesco DJ, Morris CD, Morse-Sanyal A, Mottard S, Mthethwa PG, Muñoz-Montecinos C, Murcia M, Müller M, Nakayama R, Narhari P, Nasar A, Nayak P, Neugebauer J, Nieminen J, Ntombela P, Nystrom L, O'Reilly-Harbidge S, O'Toole G, Ogura K, Oktayana MD, Oliveira V, Olivier A, Olson D, Olusunmade O, Omar M, Omran Hasan Y, Ortiz-Cruz EJ, Ozaki S, Ozaki T, Ozkan K, Pala E, Palmerini E, Panchwagh Y, Pang G, Papagelopoulos P, Papagelopoulos DP, Paraliticci G, Parizzia W, Parry M, Pate M, Peiró A, Perera J, Petersen MM, Phakathi O, Phimolsarnti R, Phiri T, Pinheiro R, Pinto Santander N, Ploegmakers J, Pollock R, Powell G, Prabowo Y, Pruthi M, Puhaindran M, Quirion J, Quirland C, Rabin E, Rachbauer A, Radhakrishnan S, Raja A, Rajalbandi R, Rajani R, Rajasekaran RB, Rajasekaran S, Rajkovic S, Ramirez MT, Ramkumar DB, Rankin KS, Ras El Abiad A, Rasappan K, Redl M, Rizzo A, Rose PS, Rosenberg A, Russell M, Salcedo Rodriguez G, Saleh A, Sambri A, Samy A, Sánchez-Maldonado M, Saputra RD, Scanferla R, Scharschmidt T, Schubert T, Scoccianti G, Segura F, Sellevold S, Shehadeh A, Shreemal B, Shumelinsky F, Siddiqi AM, Silveri C, Sinnaeve F, Smolle MA, Snyman F, Solomons M, Sommerville S, Sood SS, Spense ME, Spiegel C, Spiguel A, Staals EL, Stavropoulos NA, Steadman P, Stern S, Stevenson J, Stoppiello P, Stubbe C, Sullivan MH, Sundin N, Suntaxi Basantes FM, Szostakowski B, Szostakowski B, Tandon N, Tang X, Tepper S, Terrarossa B, Thippeswamy PB, Thorkildsen J, Tootsi K, Torner-Rubies F, Tosyali K, Traub F, Trent J, Triganjananun C, Trikoupis I, Trullols L, Tsagkozis P, Tsoi K, Tuntarattanapong P, Ulrich MN, Vainio VM, Valencia JD, van de Sande M, van der Geest I, van der Wal RJ, van Langevelde K, Velez R, Verbeke L, Verspoor FGM, Versteeg A, Vicatos G, Virk JS, Visgauss J, Vyrva O, Wafa H, Wan Faisham WI, Wang PQ, Wei R, Wennergren D, Werier J, Weschenfelder W, Williams N, Wunder J, Yildiz HY, Yonamine ES, Yonezawa H, Yousuf M, Zaghloul A, Zainul-Abidin S, Zamora T, Zuckerman L, Zumarraga JP, Özger H. A modified Delphi consensus on tenosynovial giant cell tumour and giant cell tumour of bone : a report from the Birmingham Orthopaedic Oncology Meeting (BOOM). Bone Joint J. 2026 Jun 9;108-B:1045-1051. doi: 10.1302/0301-620X.108B.BJJ-2026-0394. PMID: 42261942.

Hoberger M, Di Gioia D, Zuber RL, Völkl M, Güler SE, Jurinovic V, Albertsmeier M, Klein A, Dürr HR, Schmidt-Hegemann NS, Knösel T, Kunz WG, von Bergwelt-Baildon M, Lindner LH, Burkhard-Meier A, Berclaz LM. Machine Learning-Guided Survival Prediction and Treatment Sequencing in Advanced Soft Tissue Sarcoma Beyond Second-Line Therapy: A Retrospective Cohort Study. Oncol Ther. 2026 Jun 5. doi: 10.1007/s40487-026-00446-7. Epub ahead of print. PMID: 42247057.

Alexander Klein, Hans Roland Dürr. Benigne Knochentumoren - Zwischen harmloser Läsion und behandlungsbedürftigem Befund. Orthopädie&Rheuma 2026; 29(5) 32-39.

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